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Prevention of Colorectal Cancer by Endoscopic Polypectomy. Adenomatous polyps are precursors of most colorectal cancers, and their prevalence increases with age. The chance of detecting adenomatous polyps at colonoscopy is generally independent of the indication for the procedure. The practice of removing polyps at colonoscopy is based on the assumption that their removal prevents progression to cancer. This concept, often called the adenoma-carcinoma sequence, Colorectal cancer is one of the most common cancers in developed countries. Increasing numbers of early stage colorectal cancers and precancerous adenomatous lesions, polypoidal type lesions, and flat and depressed type lesions can be visualised and treated endoscopically thanks to endoscopic ultrasonography, high magnification chromoendoscopy and other technical advances. Polypectomy is generally considered for protuberant lesions, with both sessile and pedunculate morphology, and endoscopic mucosal resection (EMR) is indicated for superficial, flat or depressed types of lesions. Endoscopic therapy for colonic adenoma with dysplasia and early colorectal cancer is more advantageous than the conventional operative treatment, in that it is a relatively non-invasive and less costly method. However, endoscopic therapy is completely ineffective in lesions with lymph node or distant metastasis. Therefore, it is becoming more and more important to understand the correct indications and limitations of endoscopic <b>…</b>
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